EARLY SIGN

Change in attitude/lethargy

A change in personality and/or a lack of energy

Horse
EARLY SIGN

Decreased performance

Increased sluggishness compared to normal.

Clinical sign decreased performance I
EARLY SIGN

Regional hypertrichosis

Decreased or delayed shedding in specific areas (regions) of the horses body

Clinical sign hypertrichosis
EARLY SIGN

Delayed hair coat shedding

Delayed shedding of the winter coat may occur in some areas, and the summer coat may look different in these same areas.

Delayed hair coat shedding
EARLY SIGN

Loss of topline muscle

Prominent withers and/or prominent spine

Loss of topline muscle
EARLY & ADVANCED SIGN

Abnormal sweating

Increased or decreased sweating may occur.

Clinical sign hypertrichosis
EARLY & ADVANCED SIGN

Infertility

Reproductive cycles may be abnormal or absent, potentially leading to infertility.

Clinical sign infertility l
EARLY SIGN

Desmitis/tendonitis

A cause of lameness in both forelimb and hindlimb of athletic horses.

Clinical sign desmitis tendonitis r 2
EARLY SIGN

Regional adiposity

Fat deposits may appear along the crest of the neck and the tail head.

Clinical sign regional adiposity early l
EARLY SIGN

Laminitis

Inflammation of the laminae of the foot and increased tenderness.

Laminitis
EARLY SIGN

Tendon/ligament laxity

Clinical sign decreased performance
ADVANCED SIGN

Altered mentation

Sluggishness or a decreased activity

Altered mentation
ADVANCED SIGN

Exercise intolerance

Decreased ability in physical exercise

Clinical sign decreased performance
ADVANCED SIGN

Generalized hypertrichosis

Excessive hair growth over all of the body.

Horse
ADVANCED SIGN

Loss of seasonal hair coat shedding

Loss of seasonal shedding compared to herd mates or past years

Horse
ADVANCED SIGN

Topline muscle atrophy

Prominent withers, sunken shoulders and/or prominent spine

Sign Topline
ADVANCED SIGN

Rounded abdomen

The horse’s belly may have a "rounded" hay belly appearance.

Clinicalsign advanced roundedabdomen
ADVANCED SIGN

Polyuria/polydipsia

Increased urination and/or thirst.

Clinical sign polyuria polydipsia
ADVANCED SIGN

Recurrent infections

A few examples are recurring secondary skin infections, hoof abscesses, conjunctivitis and sinusitis.

Clinicalsign advanced recurrentinfections
ADVANCED SIGN

Recurrent corneal ulcers

Dry eye or recurrent injuries/infections to the outermost layer of the eye.

Clinical sign dry eye
ADVANCED SIGN

Increased mammary gland secretions

A discharge from mammary gland in a non-lactating, non-pregnant mare.

Clinical sign mammary gland
ADVANCED SIGN

Regional adiposity (bulging supraorbital fat)

Fat deposits may appear above the eyes.

Clinical sign regional adiposity
ADVANCED SIGN

Tendon and suspensory ligament laxity

Tendon laxity may be observed where the fetlock "drops" toward the ground when bearing weight.

clinicalsign advanced laxity
ADVANCED SIGN

Laminitis

Inflammation of the laminae of the foot and increased tenderness.

Laminitis

IMPORTANT SAFETY INFORMATION: PRASCEND is for use in horses only. PRASCEND has not been evaluated in breeding, pregnant, or lactating horses. Treatment with PRASCEND may cause loss of appetite. Most cases are mild. If severe, a temporary dose reduction may be necessary. Weight loss, lack of energy, and behavioral changes also may be observed. PRASCEND is contraindicated in horses with hypersensitivity to pergolide mesylate or other ergot derivatives. Not for use in humans. Do not ingest the product. PRASCEND tablets should not be crushed due to the potential for increased human exposure. Pergolide, like other ergot derivatives, may cause emesis, dizziness, lethargy or low blood pressure. Pregnant or lactating women should wear gloves when administering this product. Store this product separately away from human medicinal products and handle this product with care to avoid accidental ingestion. Keep PRASCEND in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Dogs have eaten PRASCEND tablets that were placed in food intended for horses or dropped during administration of the tablets to the horses. Adverse reactions may occur if animals other than horses ingest PRASCEND tablets. Refer to the package insert for complete product information.