PPID was previously referred to as equine Cushing's disease. PPID is one of the most common endocrine disorders in horses.³

Horses with PPID will also benefit from an overall excellent general health care along with individual nutrition recommendations from your veterinarian.

• Diet and exercise
• Proper vaccination
• Deworm regularly
• Regular care from hoof to teeth
• Body clipping, if needed

Signs of PPID vary widely and may be in the early or advanced stages. Often early clinical signs can go unrecognized. Below is a check list of both early and advanced signs of PPID. If you notice any of these signs in your horse, check with your veterinarian.

• Decreased athletic performance and/or lethargy
• Delayed shedding/decreased shedding
• Weight loss
• Cresty neck/fat pads around tail head/swollen sheath
• Excessive thirst
• Excessive urination
• Abnormal (increased or decreased) sweating
• Loss of muscle mass
• Laminitis
• Recurrent infections

PPID may be seen in all breeds of horses including ponies.² It also affects both male and female horses.²

PPID is not just an old horse disease. In rare cases, it has been seen in horses as young as 5 years of age.³

Your veterinarian will examine your horse and determine if your horse should be tested for PPID. A blood test is often performed to determine if your horse is positive for the disease.

Pergolide is considered the treatment of choice for PPID. PRASCEND is the most proven treatment available to control the clinical signs associated with PPID in horses.¹ PRASCEND treatment may cause loss of appetite. Most cases are mild. Adverse reactions may occur if animals other than horses ingest PRASCEND tablets. PRASCEND is contraindicated in horses with hypersensitivity to pergolide mesylate or other ergot derivatives. 

No. There is currently no cure for PPID. It is a chronic, lifelong disease that requires daily medical treatment. However, treatment with PRASCEND can reduce clinical signs of the disease, improving the quality of life for the affected horse.² PRASCEND has not been evaluated in breeding, pregnant or lactating horses.

PRASCEND is available only through licensed veterinarians. Your veterinarian will calculate the correct dosage based on the body weight and needs of your horse and provide you with all dosing and administration information.

PRASCEND can be hidden in an apple or treat.  PRASCEND should not be crushed due to the potential for increased human exposure. See package insert for full prescribing information.

PRASCEND comes in convenient packaging:

• Pink rectangular-shaped tablets
• Single scored tablets are easy for horse owners to divide
• Each tablet contains 1 mg of pergolide, as pergolide mesylate
• Packaged in convenient 10-tablet blister cards (plastic pockets sealed with aluminum foil)
• Blister cards are packaged in cartons containing 60 or 160 tablets

Not for use in humans. Keep this and all medications out of the reach of children. Prascend should not be crushed due to the potential for increased human exposure and care should be taken to minimize exposure when splitting tablets.

PRASCEND helps reduce the clinical signs of PPID and improve horses’ quality of life.² Treatment with PRASCEND may cause loss of appetite. Most cases are mild.

• Treatment with PRASCEND may cause loss of appetite. Most cases are mild. 
• Weight loss, lack of energy and behavioral changes also may be observed. If severe, a temporary dose reduction may be necessary. 
• PRASCEND is contraindicated in horses with hypersensitivity to pergolide mesylate or other ergot derivatives.
• PRASCEND is for use in horses only. 
• PRASCEND tablets should not be crushed due to the potential for increased human exposure. 
• Keep PRASCEND in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. Dogs have eaten PRASCEND tablets that were placed in food intended for horses or dropped during administration of the tablets to the horses.
• Adverse reactions may occur if animals other than horses ingest PRASCEND tablets.
• Refer to the product insert for complete product information.

PRASCEND has not been evaluated in breeding, pregnant, or lactating animals. As PRASCEND is a dopamine agonist, it may interfere with reproductive hormones involved in these groups of animals.

Depending on the specific clinical sign, improvement may be observed beginning within 30 days and continue through 6 months of initial treatment.⁴

Obtaining FDA approval is a strict and rigorous process. PRASCEND is manufactured according to the strict specifications set forth by the US Food & Drug Administration. PRASCEND is manufactured to provide a consistent, safe, and efficacious product.