PRASCEND is Proven and Effective

Get the most proven treatment available to control the clinical signs associated with pituitary pars intermedia dysfunction (PPID) in horses with PRASCEND.1 PRASCEND has not been evaluated in breeding, pregnant or lactating horses.

DESCRIPTION & INDICATION
About PRASCEND

PRASCEND tablets are rectangular, light-red, half-scored tablets containing 1 mg pergolide, as pergolide mesylate, a dopamine receptor agonist for oral use in horses only. It’s used for the control of clinical signs associated with PPID in horses. PRASCEND tablets should not be crushed due to the potential for increased human exposure. 

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How PRASCEND Works

Learn more about PRASCEND and how it works to help control clinical signs PPID in horses by watching this video. PRASCEND is contraindicated in horses with hypersensitivity to pergolide mesylate or other ergot derivatives. 

Conveniently Packaged
Dosage & Administration

Preserved and protected in foil blister packs, the single-scored tablets make it simple to adjust dosage. Administer orally at a starting dose of 2 mcg/kg once daily. Dosage may be adjusted to effect, not to exceed 4 mcg/kg daily. PRASCEND tablets should not be crushed due to the potential for increased human exposure and care should be taken to minimize exposure when splitting tablets.

Read More About Dosing
3 Reasons to Choose PRASCEND1
FDA Approved Created with Sketch.
CONTROLLED SIGNS
Improved clinical signs within 3 months and continued through 6 months
Dosing Created with Sketch.
PROVEN SUCCESS
3 out of 4 horses evaluated were considered treatment successes
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CLEAR IMPROVEMENT
Hypertrichosis (delayed shedding) improved in 89% of treated horses within 6 months
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IMPORTANT SAFETY INFORMATION: PRASCEND is for use in horses only. Treatment with PRASCEND may cause loss of appetite. Most cases are mild. Weight loss, lack of energy, and behavioral changes also may be observed. If severe, a temporary dose reduction may be necessary. PRASCEND has not been evaluated in breeding, pregnant or lactating horses, and may interfere with reproductive hormones in these horses. PRASCEND tablets should not be crushed due to the potential for increased human exposure. Refer to the package insert for complete product information.

SAFETY & EFFICACY
FDA-Approved as Safe and Effective1,2

A large, multi-site field study showed PRASCEND was effective in controlling clinical signs associated with PPID in horses and ponies. Additional safety monitoring was conducted during the field study, as well as a six-month margin of safety study that demonstrated PRASCEND was safe for use in horses at the labeled dosage by performing studies that used 2X the maximum dosage.1,2 Treatment with PRASCEND may cause loss of appetite. Most cases are mild. 

EFFICACY
Field Study Evaluation1,2

The PRASCEND field study showed that 76% (86 of 113 horses) of evaluable cases were treatment successes. The horses showed these results within 180 days:

  • ACTH test results returned to normal or decreased by at least 50%
  • Dexamethasone suppression test (DST) returned to normal (<1 mcg cortisol per dL) on Day 180
  • Improvement in at least one clinical sign
  • No worsening in any clinical signs or development of new signs

PRASCEND is for use in horses only. PRASCEND has not been evaluated in breeding, pregnant or lactating horses.

PRASCEND TESTIMONIAL

Watch Spirit’s PPID Story

Horseowners Stacie and Tony Richmond describe the journey of their horse Spirit with PPID, and tell their story of managing his clinical signs of PPID with PRASCEND. PRASCEND tablets should not be crushed due to the potential for increased human exposure.

TWO WAYS TO SAVE
Save $30* when you buy one 160-count box of PRASCEND

When you buy PRASCEND from your veterinarian, you can get money back by redeeming this offer.

 

*Savings in the form of a rebate offer for purchases Feb. 1 - Dec. 31, 2020.

Redeem This Offer
SAVE ON PRASCEND
Save $12* when you buy one 60-count box of PRASCEND

Redeem this offer to get money back on PRASCEND purchased from your veterinarian.

 

*Savings in the form of a rebate offer for purchases Feb. 1 - Dec. 31, 2020.

Redeem This Offer

IMPORTANT SAFETY INFORMATION: PRASCEND is for use in horses only. Treatment with PRASCEND may cause loss of appetite. Most cases are mild. Weight loss, lack of energy, and behavioral changes also may be observed. If severe, a temporary dose reduction may be necessary. PRASCEND has not been evaluated in breeding, pregnant or lactating horses, and may interfere with reproductive hormones in these horses. PRASCEND tablets should not be crushed due to the potential for increased human exposure. Refer to the package insert for complete product information.